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Selling scorpion venom online cheap from the best online suppliers Black Venom Pharmacy. Scorpion sting is the most important arachnidan envenomation that causes adult morbidity and child mortality. It remains a real health problem in many countries from tropical and subtropical regions (4, 13, 14, 15, 17, 20, 27). Scorpion venom contains small neurotoxin polypeptides consisting of low-molecular-weight simple proteins with lethal and paralytic effects (1, 3, 15, 28). Buy Moroccan Black Thick-tailed Scorpion Venom.
Several studies on scorpion stings emphasized that clinical pictures ranged from local to severe autonomic and central nervous system symptoms and also death due to cardio and respiratory failure, especially in children (5, 7, 10, 11, 12, 17, 18, 21, 22). Lethal scorpions are mostly of the Buthidae family (16, 18, 27). Buy Moroccan Black Thick-tailed Scorpion Venom Online – Reptile Venom Shop
In Turkey, scorpion envenomations are mostly caused by the genera Androctonus, Leiurus and Mesobuthus (18, 19). In the same country, A. crassicauda venom, obtained by maceration of telsons, is utilized as antigen for antivenom. This antigen has also been used against other scorpion species (23, 24). Therefore, the aim of this study was to verify the relationship between A. crassicauda venom toxicity and its telson size, weight, and storing condition. Buy Moroccan Black Thick-tailed Scorpion Venom.
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The purpose of study was to examine the cytotoxic and anti-cancer properties along with addressing the plausible pathway followed by scorpion venom to reduce cell viability in SH-SY5Y and MCF-7 cells. Following exposure of cells with scorpion venom, cytotoxicity was estimated using MTT and lactate dehydrogenase assays. Buy Moroccan Black Thick-tailed Scorpion Venom.
Apoptotic effects were measured by assessment of mitochondrial membrane potential, reactive nitrogen species, DNA fragmentation, and caspase-3 activity whereas antiproliferative effect was assayed using BrdU incorporation. Our results indicate that scorpion venom causes suppression of proliferation by arresting S-phase and induction of apoptosis through increased nitric oxide production, caspase-3 activity and depolarization of mitochondrial membrane. Buy Moroccan Black Thick-tailed Scorpion Venom.
Induction of apoptosis and arrest of DNA synthesis are critical determinant factors for development of anti cancer drugs. These properties may lead to isolation of effective molecule(s) with potential anticancer activity from scorpion venom of Androctonus crassicauda. Buy Moroccan Black Thick-tailed Scorpion Venom.
As always, identification of the species of scorpion is extremely helpful in determining prognosis. The victim should undergo careful examination and observation for systemic symptoms. Localized pain can be treated with analgesics, but CNS-depressing medications should be avoided.60,61 For severe systemic reactions, treatment can be difficult. Nearly every system can be affected, and the patient must be monitored for lethal arrhythmias, respiratory failure, and acid–base disturbances. Buy Moroccan Black Thick-tailed Scorpion Venom.
Neurological manifestations, as an isolated effect or often as a result of cardiac or pulmonary dysfunction, are associated with poor outcomes.57,62 In a retrospective study, Biswal et al.63 found that children displaying systemic reactions from scorpion sting and who received antihistamines and steroids before arrival at the hospital had a worse outcome compared to those that did not. Similarly, Curry et al.60 report that they have seen no benefit from these medications or good rationalization for their use based on the pathophysiology of scorpion venom action. Buy Moroccan Black Thick-tailed Scorpion Venom.
Gueron recommends an “intensive supportive approach directed toward the overstimulated autonomic nervous system,” i.e., control of blood pressure and pulmonary edema with agents such as hydralazine, dobutamine, prazosin, or nifedipine. Indeed, neurological symptoms often improve with this approach.57,64 Prazosin therapy in particular is recommended based on its pharmacokinetic profile,61 and those using prazosin therapy report significantly improved outcomes in children exhibiting systemic symptoms, especially if initiated early. Buy Moroccan Black Thick-tailed Scorpion Venom.
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